In this case study, we highlight the article we wrote for Microscopy Today covering the latest advancements in super-resolution microscopy to accelerate therapeutic discovery.
The project
The team at ONI (Oxford Nanoimaging Ltd, UK) commissioned us at ACBio to write a long-form article for the journal Microscopy Today. The aim of the piece was to cover the value of ONI’s single-molecule super-resolution microscopy technology and their recently launched to market Aplo Scope instrument (and sample-to-answer comprehensive workflow), while providing clear technoscientific context and a couple of examples of specific applications for the technology.
The challenge
One of the challenges of this project was ensuring that the piece did not read as a fully commercial pitch but followed a scientific article narrative that would appeal to microscopists, both new to super-resolution microscopy and active users seeking to impact their research using cutting-edge microscopy equipment. The article had to include highly technical information on super-resolution and single-molecule imaging technology and examples of its application through visually appealing data figures and imagery, aiming for around 3,500 words and 6 to 10 figures.
The work
After analysing the journal’s scope, previously published articles, and guidelines, the author, Anna Caballe, created an article outline matching key Aplo Scope value proposition pillars. At that stage, a conscious decision was made to focus on product features and benefits that enable the use of super-resolution microscopy for therapeutic discovery beyond academic or R&D labs, which would be of interest to the journal’s readership and ONI’s target markets. Upon request, the team at ONI kindly provided relevant and aesthetically pleasing images of data acquired using the Aplo Scope, ONI’s single-molecule technology, and accompanying software tools for different applications and disease areas. In parallel to the writing of the entire article, the ACBio team produced all final figures to ensure they worked in synchrony with the overall content and messaging of the article.
The outcome
After the editorial team at Microscopy Today reviewed the submitted manuscript, this was accepted for publication. The final 8-page-long article entitled “Simplifying Super-Resolution Microscopy to Accelerate Therapeutic Discovery” was published in the September 2025 issue 33 of the journal.
Read the full article at Microscope Today
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